Cargando…

Defining the ligand-dependent proximatome of the sigma 1 receptor

Sigma 1 Receptor (S1R) is a therapeutic target for a wide spectrum of pathological conditions ranging from neurodegenerative diseases to cancer and COVID-19. S1R is ubiquitously expressed throughout the visceral organs, nervous, immune and cardiovascular systems. It is proposed to function as a liga...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Jing, Veeranan-Karmegam, Rajalakshmi, Baker, Frederick C., Mysona, Barbara A., Bagchi, Pritha, Liu, Yutao, Smith, Sylvia B., Gonsalvez, Graydon B., Bollinger, Kathryn E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284605/ https://www.ncbi.nlm.nih.gov/pubmed/37351276 http://dx.doi.org/10.3389/fcell.2023.1045759

Ejemplares similares

dTtc1, a conserved tetratricopeptide repeat protein, is required for maturation of Drosophila egg chambers via its role in stabilizing electron transport chain components
por: Neiswender, Hannah, et al.
Publicado: (2023)

Sigma 1 Receptor Contributes to Astrocyte-Mediated Retinal Ganglion Cell Protection
por: Zhao, Jing, et al.
Publicado: (2022)

Sigma 1 Receptor Modulates Optic Nerve Head Astrocyte Reactivity
por: Zhao, Jing, et al.
Publicado: (2021)

Sigma 1 receptor regulates ERK activation and promotes survival of optic nerve head astrocytes
por: Zhao, Jing, et al.
Publicado: (2017)

(+)-Pentazocine Reduces NMDA-Induced Murine Retinal Ganglion Cell Death Through a σR1-Dependent Mechanism
por: Zhao, Jing, et al.
Publicado: (2016)

Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis
por: Arjunan, Pachiappan, et al.
Publicado: (2016)

Comparison of Neuroprotective Effects of Monomethylfumarate to the Sigma 1 Receptor Ligand (+)-Pentazocine in a Murine Model of Retinitis Pigmentosa
por: Xiao, Haiyan, et al.
Publicado: (2020)

Comparison of Sigma 1 Receptor Ligands SA4503 and PRE084 to (+)-Pentazocine in the rd10 Mouse Model of RP
por: Wang, Jing, et al.
Publicado: (2020)

Depletion or over-expression of Sh3px1 results in dramatic changes in cell morphology
por: Hicks, Lawrence, et al.
Publicado: (2015)

Deficiency in the endocytic adaptor proteins PHETA1/2 impairs renal and craniofacial development
por: Ates, Kristin M., et al.
Publicado: (2020)

Spatial regulation of translation through RNA localization
por: Gonsalvez, Graydon B., et al.
Publicado: (2012)

L-2-oxothiazolidine-4-carboxylic acid attenuates oxidative stress and inflammation in retinal pigment epithelium
por: Promsote, Wanwisa, et al.
Publicado: (2014)

Iron Overload Accelerates the Progression of Diabetic Retinopathy in Association with Increased Retinal Renin Expression
por: Chaudhary, Kapil, et al.
Publicado: (2018)

In vitro spermatogenesis: In search of fully defined conditions
por: Kulibin, A. Yu., et al.
Publicado: (2023)

Interplay Between Mitophagy and Apoptosis Defines a Cell Fate Upon Co-treatment of Breast Cancer Cells With a Recombinant Fragment of Human κ-Casein and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand
por: Wohlfromm, Fabian, et al.
Publicado: (2021)

High Temporal Resolution 3D Live-Cell Imaging of Budding Yeast Meiosis Defines Discontinuous Actin/Telomere-Mediated Chromosome Motion, Correlated Nuclear Envelope Deformation and Actin Filament Dynamics
por: Nozaki, Tadasu, et al.
Publicado: (2021)

Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin
por: Park, Eun Jeong, et al.
Publicado: (2020)

WNT Ligand Dependencies in Pancreatic Cancer
por: Aguilera, Kristina Y., et al.
Publicado: (2021)

Editorial: Novel ligands and receptors in endocrine disorders
por: Zhao, Huashan, et al.
Publicado: (2023)

Defining Skin Fibroblastic Cell Types Beyond CD90
por: Jiang, Dongsheng, et al.
Publicado: (2018)

Freeze-Dried Extracellular Vesicles From Adipose-Derived Stem Cells Prevent Hypoxia-Induced Muscle Cell Injury
por: El Baradie, Khairat Bahgat Youssef, et al.
Publicado: (2020)

EpCAM-Mediated Cellular Plasticity Promotes Radiation Resistance and Metastasis in Breast Cancer
por: Mal, Arijit, et al.
Publicado: (2021)

Defining the Emerging Blood System During Development at Single-Cell Resolution
por: Karlsson, Göran, et al.
Publicado: (2021)

Proteomic analysis defines the interactome of telomerase in the protozoan parasite, Trypanosoma brucei
por: Davis, Justin A., et al.
Publicado: (2023)

Indolethylamine-N-Methyltransferase Inhibits Proliferation and Promotes Apoptosis of Human Prostate Cancer Cells: A Mechanistic Exploration
por: Jianfeng, Wang, et al.
Publicado: (2022)

Multiple Poses and Thermodynamics of Ligands Targeting Protein Surfaces: The Case of Furosemide Binding to mitoNEET in Aqueous Solution
por: Hoang, Linh Gia, et al.
Publicado: (2022)

Protein Expression Landscape Defines the Formation Potential of Mouse Blastoids From EPSCs
por: Min, Zheying, et al.
Publicado: (2022)

Expression Patterns of Glycosylation Regulators Define Tumor Microenvironment and Immunotherapy in Gastric Cancer
por: Li, Fang, et al.
Publicado: (2022)

Source and Impact of the EGF Family of Ligands on Intestinal Stem Cells
por: Abud, Helen E., et al.
Publicado: (2021)

Role of Sigma 1 Receptor in Retinal Degeneration of the Ins2(Akita/+) Murine Model of Diabetic Retinopathy
por: Wang, Jing, et al.
Publicado: (2016)

The antigenic determinant that defines thymic nurse cells is expressed by thymic epithelial progenitor cells
por: Chilukuri, Rajendra V. E., et al.
Publicado: (2014)

Single-Cell RNA Sequencing Defines the Regulation of Spermatogenesis by Sertoli-Cell Androgen Signaling
por: Cao, Congcong, et al.
Publicado: (2021)

The RUNX1b Isoform Defines Hemogenic Competency in Developing Human Endothelial Cells
por: Menegatti, Sara, et al.
Publicado: (2021)

Prolyl Isomerization-Mediated Conformational Changes Define ATR Subcellular Compartment-Specific Functions
por: Biswas, Himadri, et al.
Publicado: (2022)

Ligand-bound integrin αvβ6 internalisation and trafficking
por: Meecham, Amelia, et al.
Publicado: (2022)

Activation of Sigma 1 Receptor Extends Survival of Cones and Improves Visual Acuity in a Murine Model of Retinitis Pigmentosa
por: Wang, Jing, et al.
Publicado: (2019)

Absence of Sigma 1 Receptor Accelerates Photoreceptor Cell Death in a Murine Model of Retinitis Pigmentosa
por: Wang, Jing, et al.
Publicado: (2017)

Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL
por: Artykov, Artem A., et al.
Publicado: (2021)

Membrane Tethering Potency of Rab-Family Small GTPases Is Defined by the C-Terminal Hypervariable Regions
por: Ueda, Sanae, et al.
Publicado: (2020)

Cross-Talk of Focal Adhesion-Related Gene Defines Prognosis and the Immune Microenvironment in Gastric Cancer
por: Mao, Deli, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rnd7fcmm6qbq1qkepsrpg5karh