Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases

The expression of hormone receptors (estrogen and progesterone) and human epidermal growth factor receptor-2 (HER2) has been used for both therapeutic and prognostic purposes in the management of breast cancer. The presence of a discordant receptor status complicates the approach to treatment in pat...

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Detalles Bibliográficos
Autores principales: Ojo, Ademola S., Shittu, Adedoyin, Amadife, Stacy, Jackson, Devon, Grantham, Mica, Ali, Ahmed, Sarma, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284639/
https://www.ncbi.nlm.nih.gov/pubmed/37350805
http://dx.doi.org/10.14740/wjon1603
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author Ojo, Ademola S.
Shittu, Adedoyin
Amadife, Stacy
Jackson, Devon
Grantham, Mica
Ali, Ahmed
Sarma, Ravi
author_facet Ojo, Ademola S.
Shittu, Adedoyin
Amadife, Stacy
Jackson, Devon
Grantham, Mica
Ali, Ahmed
Sarma, Ravi
author_sort Ojo, Ademola S.
collection PubMed
description The expression of hormone receptors (estrogen and progesterone) and human epidermal growth factor receptor-2 (HER2) has been used for both therapeutic and prognostic purposes in the management of breast cancer. The presence of a discordant receptor status complicates the approach to treatment in patients with synchronous bilateral breast cancer. We describe the case of a 45-year-old female with synchronous bilateral breast cancer with a triple-negative tumor and a contralateral HER2-positive tumor and discussed the impact of this on the approach to therapeutic management.
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spelling pubmed-102846392023-06-22 Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases Ojo, Ademola S. Shittu, Adedoyin Amadife, Stacy Jackson, Devon Grantham, Mica Ali, Ahmed Sarma, Ravi World J Oncol Case Report The expression of hormone receptors (estrogen and progesterone) and human epidermal growth factor receptor-2 (HER2) has been used for both therapeutic and prognostic purposes in the management of breast cancer. The presence of a discordant receptor status complicates the approach to treatment in patients with synchronous bilateral breast cancer. We describe the case of a 45-year-old female with synchronous bilateral breast cancer with a triple-negative tumor and a contralateral HER2-positive tumor and discussed the impact of this on the approach to therapeutic management. Elmer Press 2023-06 2023-06-11 /pmc/articles/PMC10284639/ /pubmed/37350805 http://dx.doi.org/10.14740/wjon1603 Text en Copyright 2023, Ojo et al. https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ojo, Ademola S.
Shittu, Adedoyin
Amadife, Stacy
Jackson, Devon
Grantham, Mica
Ali, Ahmed
Sarma, Ravi
Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases
title Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases
title_full Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases
title_fullStr Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases
title_full_unstemmed Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases
title_short Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases
title_sort synchronous bilateral breast cancer with discordant receptor status: treating one patient but two diseases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284639/
https://www.ncbi.nlm.nih.gov/pubmed/37350805
http://dx.doi.org/10.14740/wjon1603
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