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Does Liver Resection Remain a Viable Option in Patients With Pyogenic Liver Abscess? A Single-Center Experience

Pyogenic liver abscesses (PLAs) are relatively rare but often fatal if left untreated. Antibiotic therapy combined with percutaneous procedures has replaced surgery as the cornerstone of treatment. However, open surgical drainage or liver resection may be a last resort. This study aimed to review ou...

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Autores principales: Obed, Aiman, Abuassi, Mohammad, Alsakarneh, Saqr, Jaber, Fouad, Fakhri, Mahmoud, Abufares, Fadi, Bashir, Abdalla, Syam, Mahmood, Jarrad, Anwar, Abdelhadi, Ody, Ghoz, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284645/
https://www.ncbi.nlm.nih.gov/pubmed/37351080
http://dx.doi.org/10.14740/gr1611
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author Obed, Aiman
Abuassi, Mohammad
Alsakarneh, Saqr
Jaber, Fouad
Fakhri, Mahmoud
Abufares, Fadi
Bashir, Abdalla
Syam, Mahmood
Jarrad, Anwar
Abdelhadi, Ody
Ghoz, Hassan
author_facet Obed, Aiman
Abuassi, Mohammad
Alsakarneh, Saqr
Jaber, Fouad
Fakhri, Mahmoud
Abufares, Fadi
Bashir, Abdalla
Syam, Mahmood
Jarrad, Anwar
Abdelhadi, Ody
Ghoz, Hassan
author_sort Obed, Aiman
collection PubMed
description Pyogenic liver abscesses (PLAs) are relatively rare but often fatal if left untreated. Antibiotic therapy combined with percutaneous procedures has replaced surgery as the cornerstone of treatment. However, open surgical drainage or liver resection may be a last resort. This study aimed to review our experience in treating PLA, with a focus on the conditions requiring partial liver resection as the last viable curative option. Medical records of patients with PLA admitted to Jordan Hospital between October 2014 through October 2020 were retrospectively reviewed. Medical and demographic data of all 43 patients admitted to our facility with a diagnosis of PLA were extracted. We reviewed these patients and extracted the cases that required surgical intervention. Four (three males and one female) of the 43 patients with PLA required surgical intervention. The underlying causes of liver abscesses were as follows: one traumatic due to shrapnel injury from an explosion, one following chemoembolization for hepatocellular carcinoma, and two patients with no apparent etiology. All patients were diagnosed with a computed tomography (CT) scan of the abdomen and pelvis with intravenous contrast. Two patients had negative cultures. All patients received broad-spectrum antibiotics, and all underwent CT- or ultrasound-guided percutaneous drainage or aspiration. All four patients required partial hepatic resection due to treatment failure or inaccessible percutaneous procedures with clinical improvement. Although antimicrobial and interventional therapy remains the primary treatment option in PLA, the surgical option with open surgical drainage or partial liver resection remains viable and curative in selected patients.
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spelling pubmed-102846452023-06-22 Does Liver Resection Remain a Viable Option in Patients With Pyogenic Liver Abscess? A Single-Center Experience Obed, Aiman Abuassi, Mohammad Alsakarneh, Saqr Jaber, Fouad Fakhri, Mahmoud Abufares, Fadi Bashir, Abdalla Syam, Mahmood Jarrad, Anwar Abdelhadi, Ody Ghoz, Hassan Gastroenterology Res Case Report Pyogenic liver abscesses (PLAs) are relatively rare but often fatal if left untreated. Antibiotic therapy combined with percutaneous procedures has replaced surgery as the cornerstone of treatment. However, open surgical drainage or liver resection may be a last resort. This study aimed to review our experience in treating PLA, with a focus on the conditions requiring partial liver resection as the last viable curative option. Medical records of patients with PLA admitted to Jordan Hospital between October 2014 through October 2020 were retrospectively reviewed. Medical and demographic data of all 43 patients admitted to our facility with a diagnosis of PLA were extracted. We reviewed these patients and extracted the cases that required surgical intervention. Four (three males and one female) of the 43 patients with PLA required surgical intervention. The underlying causes of liver abscesses were as follows: one traumatic due to shrapnel injury from an explosion, one following chemoembolization for hepatocellular carcinoma, and two patients with no apparent etiology. All patients were diagnosed with a computed tomography (CT) scan of the abdomen and pelvis with intravenous contrast. Two patients had negative cultures. All patients received broad-spectrum antibiotics, and all underwent CT- or ultrasound-guided percutaneous drainage or aspiration. All four patients required partial hepatic resection due to treatment failure or inaccessible percutaneous procedures with clinical improvement. Although antimicrobial and interventional therapy remains the primary treatment option in PLA, the surgical option with open surgical drainage or partial liver resection remains viable and curative in selected patients. Elmer Press 2023-06 2023-06-11 /pmc/articles/PMC10284645/ /pubmed/37351080 http://dx.doi.org/10.14740/gr1611 Text en Copyright 2023, Obed et al. https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Obed, Aiman
Abuassi, Mohammad
Alsakarneh, Saqr
Jaber, Fouad
Fakhri, Mahmoud
Abufares, Fadi
Bashir, Abdalla
Syam, Mahmood
Jarrad, Anwar
Abdelhadi, Ody
Ghoz, Hassan
Does Liver Resection Remain a Viable Option in Patients With Pyogenic Liver Abscess? A Single-Center Experience
title Does Liver Resection Remain a Viable Option in Patients With Pyogenic Liver Abscess? A Single-Center Experience
title_full Does Liver Resection Remain a Viable Option in Patients With Pyogenic Liver Abscess? A Single-Center Experience
title_fullStr Does Liver Resection Remain a Viable Option in Patients With Pyogenic Liver Abscess? A Single-Center Experience
title_full_unstemmed Does Liver Resection Remain a Viable Option in Patients With Pyogenic Liver Abscess? A Single-Center Experience
title_short Does Liver Resection Remain a Viable Option in Patients With Pyogenic Liver Abscess? A Single-Center Experience
title_sort does liver resection remain a viable option in patients with pyogenic liver abscess? a single-center experience
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284645/
https://www.ncbi.nlm.nih.gov/pubmed/37351080
http://dx.doi.org/10.14740/gr1611
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