Genome expansion by a CRISPR trimmer-integrase

CRISPR–Cas adaptive immune systems capture DNA fragments from invading mobile genetic elements and integrate them into the host genome to provide a template for RNA-guided immunity(1). CRISPR systems maintain genome integrity and avoid autoimmunity by distinguishing between self and non-self, a proc...

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Detalles Bibliográficos
Autores principales: Wang, Joy Y., Tuck, Owen T., Skopintsev, Petr, Soczek, Katarzyna M., Li, Gary, Al-Shayeb, Basem, Zhou, Julia, Doudna, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284694/
https://www.ncbi.nlm.nih.gov/pubmed/37316664
http://dx.doi.org/10.1038/s41586-023-06178-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284694/
https://www.ncbi.nlm.nih.gov/pubmed/37316664
http://dx.doi.org/10.1038/s41586-023-06178-2

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