In situ tumour arrays reveal early environmental control of cancer immunity

The immune phenotype of a tumour is a key predictor of its response to immunotherapy(1–4). Patients who respond to checkpoint blockade generally present with immune-inflamed(5–7) tumours that are highly infiltrated by T cells. However, not all inflamed tumours respond to therapy, and even lower resp...

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Detalles Bibliográficos
Autores principales: Ortiz-Muñoz, Guadalupe, Brown, Markus, Carbone, Catherine B., Pechuan-Jorge, Ximo, Rouilly, Vincent, Lindberg, Henrik, Ritter, Alex T., Raghupathi, Gautham, Sun, Qianbo, Nicotra, Tess, Mantri, Shreya R., Yang, Angela, Doerr, Jonas, Nagarkar, Deepti, Darmanis, Spyros, Haley, Benjamin, Mariathasan, Sanjeev, Wang, Yulei, Gomez-Roca, Carlos, de Andrea, Carlos Eduardo, Spigel, David, Wu, Thomas, Delamarre, Lelia, Schöneberg, Johannes, Modrusan, Zora, Price, Richard, Turley, Shannon J., Mellman, Ira, Moussion, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284705/
https://www.ncbi.nlm.nih.gov/pubmed/37258670
http://dx.doi.org/10.1038/s41586-023-06132-2

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