Improving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters

Recombinant adeno-associated viral vectors (AAVs) are an effective system for gene transfer. AAV serotype 2 (AAV2) is commonly used to deliver transgenes to retinal ganglion cells (RGCs) via intravitreal injection. The AAV serotype however is not the only factor contributing to the effectiveness of...

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Detalles Bibliográficos
Autores principales: Nieuwenhuis, Bart, Laperrousaz, Elise, Tribble, James R., Verhaagen, Joost, Fawcett, James W., Martin, Keith R., Williams, Pete A., Osborne, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284706/
https://www.ncbi.nlm.nih.gov/pubmed/36635457
http://dx.doi.org/10.1038/s41434-022-00380-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284706/
https://www.ncbi.nlm.nih.gov/pubmed/36635457
http://dx.doi.org/10.1038/s41434-022-00380-z

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