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Pyrethroid-treated bed nets impair blood feeding performance in insecticide resistant mosquitoes
The blood feeding performance of female mosquitoes directly impacts their ability to transmit malaria. Yet their host seeking and blood feeding behaviours in the presence of insecticide-treated nets (ITNs) are still poorly understood. This work explores how both insecticide resistant and susceptible...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284836/ https://www.ncbi.nlm.nih.gov/pubmed/37344580 http://dx.doi.org/10.1038/s41598-023-35958-z |
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author | Barreaux, Priscille Ranson, Hilary Foster, Geraldine M. McCall, Philip J. |
author_facet | Barreaux, Priscille Ranson, Hilary Foster, Geraldine M. McCall, Philip J. |
author_sort | Barreaux, Priscille |
collection | PubMed |
description | The blood feeding performance of female mosquitoes directly impacts their ability to transmit malaria. Yet their host seeking and blood feeding behaviours in the presence of insecticide-treated nets (ITNs) are still poorly understood. This work explores how both insecticide resistant and susceptible Anopheles gambiae s.l. mosquitoes interact with pyrethroid nets (PermaNet 2.0 or Olyset net) or an untreated net (UTN) while attempting to blood feed on a human arm. Regardless of mosquito resistance status, the ITNs did not efficiently prevent host searching but reduced blood feeding success by 34.1 (29.31–38.95) %. The Permanet and Olyset net reduced to 227.5 (208.19–246.77) sec and 235.9 (214.03–257.74) sec the average blood feeding duration from 369.9 (342.78–397.04) sec with the UTN. The ingested blood volume was on average 22% lower for all mosquitoes exposed to insecticide. When feeding through ITNs, the blood volume flow rate of the susceptible strain increased by 35%, but no significant difference was found in the resistant strain. Thus, whilst the presence of the insecticide in ITNs reduced mosquito blood feeding success and blood volume, the mosquito’s ability to respond by accelerating her rate of blood ingestion may further reduce the impact of ITNs on resistant mosquitoes. |
format | Online Article Text |
id | pubmed-10284836 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-102848362023-06-23 Pyrethroid-treated bed nets impair blood feeding performance in insecticide resistant mosquitoes Barreaux, Priscille Ranson, Hilary Foster, Geraldine M. McCall, Philip J. Sci Rep Article The blood feeding performance of female mosquitoes directly impacts their ability to transmit malaria. Yet their host seeking and blood feeding behaviours in the presence of insecticide-treated nets (ITNs) are still poorly understood. This work explores how both insecticide resistant and susceptible Anopheles gambiae s.l. mosquitoes interact with pyrethroid nets (PermaNet 2.0 or Olyset net) or an untreated net (UTN) while attempting to blood feed on a human arm. Regardless of mosquito resistance status, the ITNs did not efficiently prevent host searching but reduced blood feeding success by 34.1 (29.31–38.95) %. The Permanet and Olyset net reduced to 227.5 (208.19–246.77) sec and 235.9 (214.03–257.74) sec the average blood feeding duration from 369.9 (342.78–397.04) sec with the UTN. The ingested blood volume was on average 22% lower for all mosquitoes exposed to insecticide. When feeding through ITNs, the blood volume flow rate of the susceptible strain increased by 35%, but no significant difference was found in the resistant strain. Thus, whilst the presence of the insecticide in ITNs reduced mosquito blood feeding success and blood volume, the mosquito’s ability to respond by accelerating her rate of blood ingestion may further reduce the impact of ITNs on resistant mosquitoes. Nature Publishing Group UK 2023-06-21 /pmc/articles/PMC10284836/ /pubmed/37344580 http://dx.doi.org/10.1038/s41598-023-35958-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Barreaux, Priscille Ranson, Hilary Foster, Geraldine M. McCall, Philip J. Pyrethroid-treated bed nets impair blood feeding performance in insecticide resistant mosquitoes |
title | Pyrethroid-treated bed nets impair blood feeding performance in insecticide resistant mosquitoes |
title_full | Pyrethroid-treated bed nets impair blood feeding performance in insecticide resistant mosquitoes |
title_fullStr | Pyrethroid-treated bed nets impair blood feeding performance in insecticide resistant mosquitoes |
title_full_unstemmed | Pyrethroid-treated bed nets impair blood feeding performance in insecticide resistant mosquitoes |
title_short | Pyrethroid-treated bed nets impair blood feeding performance in insecticide resistant mosquitoes |
title_sort | pyrethroid-treated bed nets impair blood feeding performance in insecticide resistant mosquitoes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284836/ https://www.ncbi.nlm.nih.gov/pubmed/37344580 http://dx.doi.org/10.1038/s41598-023-35958-z |
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