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How soluble misfolded proteins bypass chaperones at the molecular level

Subpopulations of soluble, misfolded proteins can bypass chaperones within cells. The extent of this phenomenon and how it happens at the molecular level are unknown. Through a meta-analysis of the experimental literature we find that in all quantitative protein refolding studies there is always a s...

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Detalles Bibliográficos
Autores principales:	Halder, Ritaban, Nissley, Daniel A., Sitarik, Ian, Jiang, Yang, Rao, Yiyun, Vu, Quyen V., Li, Mai Suan, Pritchard, Justin, O’Brien, Edward P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284856/ https://www.ncbi.nlm.nih.gov/pubmed/37344452 http://dx.doi.org/10.1038/s41467-023-38962-z

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