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TRPS1 regulates the opposite effect of progesterone via RANKL in endometrial carcinoma and breast carcinoma

Medroxyprogesterone (MPA) has therapeutic effect on endometrial carcinoma (EC), while it could promote the carcinogenesis of breast cancer (BC) by activating receptor activator of NF-kB ligand (RANKL). However, the selective mechanism of MPA in endometrium and breast tissue remains obscure. Multiomi...

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Detalles Bibliográficos
Autores principales: Yang, Linlin, Fan, Qiong, Wang, Jing, Yang, Xiaoming, Yuan, Jiangjing, Li, Yuhong, Sun, Xiao, Wang, Yudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284899/
https://www.ncbi.nlm.nih.gov/pubmed/37344459
http://dx.doi.org/10.1038/s41420-023-01484-0