Mechanisms of preferential bone formation in myeloma bone lesions by proteasome inhibitors

Proteasome inhibitors (PIs) can preferentially restore bone in bone-defective lesions of patients with multiple myeloma (MM) who respond favorably to these drugs. Most prior in vitro studies on PIs used continuous exposure to low PI concentrations, although pharmacokinetic analysis in patients has s...

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Detalles Bibliográficos
Autores principales: Nakaue, Emiko, Teramachi, Jumpei, Tenshin, Hirofumi, Hiasa, Masahiro, Harada, Takeshi, Oda, Asuka, Inoue, Yusuke, Shimizu, So, Higa, Yoshiki, Sogabe, Kimiko, Oura, Masahiro, Hara, Tomoyo, Sumitani, Ryohei, Maruhashi, Tomoko, Yamagami, Hiroki, Endo, Itsuro, Tanaka, Eiji, Abe, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284934/
https://www.ncbi.nlm.nih.gov/pubmed/37039914
http://dx.doi.org/10.1007/s12185-023-03601-2

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