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Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition

Chronic thromboembolic pulmonary hypertension is a rare but life-threatening complication of long-term central venous catheters (CVC) in children. However, evidence in terms of potential treatment strategies and outcome data remains scarce. We describe two cases of CVC-related thrombosis (Hickman-ca...

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Autores principales: Hanuna, Maja, Pattathu, Joseph, Buech, Joscha, Kamla, Christine, Kneidinger, Nikolaus, Behr, Juergen, Milger, Katrin, Veit, Tobias, Nagel, Marina, Abicht, Jan, Dalla-Pozza, Robert, Fischer, Marcus, Jakob, Andre, Hermann, Matthias, Schramm, Rene, Rosenthal, Laura L., Haas, Nikolaus, Hörer, Jürgen, Hagl, Christian, Michel, Sebastian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285210/
https://www.ncbi.nlm.nih.gov/pubmed/37363098
http://dx.doi.org/10.3389/fcvm.2023.1198204
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author Hanuna, Maja
Pattathu, Joseph
Buech, Joscha
Kamla, Christine
Kneidinger, Nikolaus
Behr, Juergen
Milger, Katrin
Veit, Tobias
Nagel, Marina
Abicht, Jan
Dalla-Pozza, Robert
Fischer, Marcus
Jakob, Andre
Hermann, Matthias
Schramm, Rene
Rosenthal, Laura L.
Haas, Nikolaus
Hörer, Jürgen
Hagl, Christian
Michel, Sebastian G.
author_facet Hanuna, Maja
Pattathu, Joseph
Buech, Joscha
Kamla, Christine
Kneidinger, Nikolaus
Behr, Juergen
Milger, Katrin
Veit, Tobias
Nagel, Marina
Abicht, Jan
Dalla-Pozza, Robert
Fischer, Marcus
Jakob, Andre
Hermann, Matthias
Schramm, Rene
Rosenthal, Laura L.
Haas, Nikolaus
Hörer, Jürgen
Hagl, Christian
Michel, Sebastian G.
author_sort Hanuna, Maja
collection PubMed
description Chronic thromboembolic pulmonary hypertension is a rare but life-threatening complication of long-term central venous catheters (CVC) in children. However, evidence in terms of potential treatment strategies and outcome data remains scarce. We describe two cases of CVC-related thrombosis (Hickman-catheter) complicated by recurrent pulmonary emboli. One patient experienced a complete thromboembolic obstruction of the right pulmonary artery with normal pulmonary pressures and the second patient suffered from a central thromboembolic obstruction of both pulmonary arteries associated with severe pulmonary hypertension. Both patients successfully underwent surgical thromboendarterectomy with deep hypothermic circulatory arrest.
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spelling pubmed-102852102023-06-23 Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition Hanuna, Maja Pattathu, Joseph Buech, Joscha Kamla, Christine Kneidinger, Nikolaus Behr, Juergen Milger, Katrin Veit, Tobias Nagel, Marina Abicht, Jan Dalla-Pozza, Robert Fischer, Marcus Jakob, Andre Hermann, Matthias Schramm, Rene Rosenthal, Laura L. Haas, Nikolaus Hörer, Jürgen Hagl, Christian Michel, Sebastian G. Front Cardiovasc Med Cardiovascular Medicine Chronic thromboembolic pulmonary hypertension is a rare but life-threatening complication of long-term central venous catheters (CVC) in children. However, evidence in terms of potential treatment strategies and outcome data remains scarce. We describe two cases of CVC-related thrombosis (Hickman-catheter) complicated by recurrent pulmonary emboli. One patient experienced a complete thromboembolic obstruction of the right pulmonary artery with normal pulmonary pressures and the second patient suffered from a central thromboembolic obstruction of both pulmonary arteries associated with severe pulmonary hypertension. Both patients successfully underwent surgical thromboendarterectomy with deep hypothermic circulatory arrest. Frontiers Media S.A. 2023-06-08 /pmc/articles/PMC10285210/ /pubmed/37363098 http://dx.doi.org/10.3389/fcvm.2023.1198204 Text en © 2023 Hanuna, Pattathu, Buech, Kamla, Kneidinger, Behr, Milger, Veit, Nagel, Abicht, Dalla-Pozza, Fischer, Jakob, Hermann, Schramm, Rosenthal, Haas, Hörer, Hagl and Michel. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Hanuna, Maja
Pattathu, Joseph
Buech, Joscha
Kamla, Christine
Kneidinger, Nikolaus
Behr, Juergen
Milger, Katrin
Veit, Tobias
Nagel, Marina
Abicht, Jan
Dalla-Pozza, Robert
Fischer, Marcus
Jakob, Andre
Hermann, Matthias
Schramm, Rene
Rosenthal, Laura L.
Haas, Nikolaus
Hörer, Jürgen
Hagl, Christian
Michel, Sebastian G.
Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition
title Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition
title_full Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition
title_fullStr Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition
title_full_unstemmed Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition
title_short Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition
title_sort case report: central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285210/
https://www.ncbi.nlm.nih.gov/pubmed/37363098
http://dx.doi.org/10.3389/fcvm.2023.1198204
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