Induced pluripotent stem cell model revealed impaired neurovascular interaction in genetic small vessel disease Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy

INTRODUCTION: Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is the most common genetic small vessel disease caused by variants in the NOTCH3 gene. Patients with CADASIL experience recurrent strokes, developing into cognitive defect and vascular...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjun, Zhao, Xiangjun, Qi, Xuewei, Kimber, Susan J., Hooper, Nigel M., Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285224/
https://www.ncbi.nlm.nih.gov/pubmed/37361999
http://dx.doi.org/10.3389/fncel.2023.1195470

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