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Immediate early response 3 gene promotes aggressive progression and autophagy of AML by negatively regulating AKT/mTOR

BACKGROUND: Immediate early response 3 (IER3) plays a vital role in many tumors. This study aims to explore the function and mechanism of IER3 in Acute myeloid leukemia (AML). METHODS: The expression of IER3 in AML was performed by bioinformatics analysis. CCK-8 proliferation assay, flow cytometry c...

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Detalles Bibliográficos
Autores principales: Chen, Yimin, Huang, Zhenqian, Chen, Shuyi, Tan, Li, He, Lang, Yuan, Danyun, Zheng, Lixia, Zhong, Jing hua, Li, Anqiao, Zhang, Heng, Tan, Huo, Xu, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285281/
https://www.ncbi.nlm.nih.gov/pubmed/37327583
http://dx.doi.org/10.1016/j.tranon.2023.101711