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Immune cell proportions correlate with clinicogenomic features and ex vivo drug responses in acute myeloid leukemia

INTRODUCTION: The implementation of small-molecule and immunotherapies in acute myeloid leukemia (AML) has been challenging due to genetic and epigenetic variability amongst patients. There are many potential mechanisms by which immune cells could influence small-molecule or immunotherapy responses,...

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Detalles Bibliográficos
Autores principales: Romine, Kyle A., Bottomly, Daniel, Yashar, William, Long, Nicola, Viehdorfer, Matthew, McWeeney, Shannon K., Tyner, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285384/
https://www.ncbi.nlm.nih.gov/pubmed/37361575
http://dx.doi.org/10.3389/fonc.2023.1192829