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In silico identification and characterization of the SNPs in the human ASTL gene and their probable role in female infertility

Ovastacin (ASTL), a zinc metalloprotease, is released from a fertilized egg during exocytosis of cortical granules which occurs minutes after the sperm and egg fuse. ASTL cleaves ZP2, one of the four primary glycoproteins of human zona pellucida, and this cleavage prevents polyspermy, causes zona pe...

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Detalles Bibliográficos
Autores principales:	Suri, Kapali, Rajput, Neha, Sharma, Priya, Omble, Aishwarya D., Kulkarni, Kiran, Gahlay, Gagandeep K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285486/ https://www.ncbi.nlm.nih.gov/pubmed/37363721 http://dx.doi.org/10.3389/fcell.2023.1151672

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