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Antithrombin lowering in hemophilia: a closer look at fitusiran
Thrombin is a key enzyme in the maintenance of normal hemostatic function and is the central product of an interconnected set of simultaneously occurring cellular and proteolytic events. Antithrombin (AT) is a natural anticoagulant that downregulates different components of the clotting process, par...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285540/ https://www.ncbi.nlm.nih.gov/pubmed/37358958 http://dx.doi.org/10.1016/j.rpth.2023.100179 |