Using a Clinically Interpretable End Point Composed of Multiple Outcomes to Evaluate Totality of Treatment Effect in Comparative Oncology Studies

This cohort study demonstrates how to use cumulative event count curves to create a clinically meaningful end point by simultaneously considering recurrence, progression, and survival times from the individual patient.

Detalles Bibliográficos
Autores principales: Wang, Xiaofei, McCaw, Zachary R., Tian, Lu, Stinchcombe, Thomas E., Vokes, Everett, Ludmir, Ethan B., Wei, Lee-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285578/
https://www.ncbi.nlm.nih.gov/pubmed/37342044
http://dx.doi.org/10.1001/jamanetworkopen.2023.19055
Descripción
Sumario:This cohort study demonstrates how to use cumulative event count curves to create a clinically meaningful end point by simultaneously considering recurrence, progression, and survival times from the individual patient.

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