Predicting the number of lifetime divisions for hematopoietic stem cells from telomere length measurements

How many times does a typical hematopoietic stem cell (HSC) divide to maintain a daily production of over [Formula: see text] blood cells over a human lifetime? It has been predicted that relatively few, slowly dividing HSCs occupy the top of the hematopoietic hierarchy. However, tracking HSCs direc...

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Detalles Bibliográficos
Autores principales: Boyle, Cole, Lansdorp, Peter M., Edelstein-Keshet, Leah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285640/
https://www.ncbi.nlm.nih.gov/pubmed/37360685
http://dx.doi.org/10.1016/j.isci.2023.107053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285640/
https://www.ncbi.nlm.nih.gov/pubmed/37360685
http://dx.doi.org/10.1016/j.isci.2023.107053

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