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Predicting the number of lifetime divisions for hematopoietic stem cells from telomere length measurements
How many times does a typical hematopoietic stem cell (HSC) divide to maintain a daily production of over [Formula: see text] blood cells over a human lifetime? It has been predicted that relatively few, slowly dividing HSCs occupy the top of the hematopoietic hierarchy. However, tracking HSCs direc...
Autores principales: | Boyle, Cole, Lansdorp, Peter M., Edelstein-Keshet, Leah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285640/ https://www.ncbi.nlm.nih.gov/pubmed/37360685 http://dx.doi.org/10.1016/j.isci.2023.107053 |
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