A New Preclinical Model of Retinitis Pigmentosa Due to Pde6g Deficiency

PURPOSE: Retinitis pigmentosa (RP) is the most common cause of inherited blindness, with onset occurring as early as 4 years of age in certain rare but severe forms caused by mutations in the gamma subunit of phosphodiesterase 6 (PDE6). Studies in humans and mice have shown that RP pathology begins...

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Detalles Bibliográficos
Autores principales: Jentzsch, Michelle Carmen, Tsang, Stephen H., Koch, Susanne Friederike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285708/
https://www.ncbi.nlm.nih.gov/pubmed/37363133
http://dx.doi.org/10.1016/j.xops.2023.100332

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