A Multi-Modal Approach to Islet and Pancreas Transplantation With Calcineurin-Sparing Immunosuppression Maintains Long-Term Insulin Independence in Patients With Type I Diabetes

Long-term success in beta-cell replacement remains limited by the toxic effects of calcineurin inhibitors (CNI) on beta-cells and renal function. We report a multi-modal approach including islet and pancreas-after-islet (PAI) transplant utilizing calcineurin-sparing immunosuppression. Ten consecutiv...

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Detalles Bibliográficos
Autores principales: Wisel, Steven A., Posselt, Andrew M., Szot, Gregory L., Nunez, Miguel, Santos-Parker, Keli, Gardner, James M., Worner, Giulia, Roll, Garrett R., Syed, Shareef, Kelly, Yvonne, Ward, Casey, Tavakol, Medhi, Johnson, Kristina, Masharani, Umesh, Stock, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Health Archive
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285771/
https://www.ncbi.nlm.nih.gov/pubmed/37359825
http://dx.doi.org/10.3389/ti.2023.11367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285771/
https://www.ncbi.nlm.nih.gov/pubmed/37359825
http://dx.doi.org/10.3389/ti.2023.11367

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