Cargando…

Histone Deacetylase Inhibition and Autophagy Modulation Induces a Synergistic Antiproliferative Effect and Cell Death in Cholangiocarcinoma Cells

[Image: see text] Cholangiocarcinoma, also known as biliary tract cancer, is an aggressive adenocarcinoma arising from epithelial cells lining the intra- and extrahepatic biliary system. The effects of autophagy modulators and histone deacetylase (HDAC) inhibitors in cholangiocarcinoma are not fully...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yenigül, Münevver, Gencer Akçok, Emel Başak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285991/ https://www.ncbi.nlm.nih.gov/pubmed/37360445 http://dx.doi.org/10.1021/acsomega.3c01317

Ejemplares similares

Autophagy-related cell death by pan-histone deacetylase inhibition in liver cancer
por: Di Fazio, Pietro, et al.
Publicado: (2016)

Role of Histone Deacetylases in Carcinogenesis: Potential Role in Cholangiocarcinoma
por: Pant, Kishor, et al.
Publicado: (2020)

Histone deacetylase 3 overexpression in human cholangiocarcinoma and promotion of cell growth via apoptosis inhibition
por: Yin, Yuyao, et al.
Publicado: (2017)

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer
por: Del Bufalo, Donatella, et al.
Publicado: (2014)

Krüppel-like factor 9 and histone deacetylase inhibitors synergistically induce cell death in glioblastoma stem-like cells
por: Tung, Brian, et al.
Publicado: (2018)

Inhibition of Histone Methyltransferase, Histone Deacetylase, and β-Catenin Synergistically Enhance the Cardiac Potential of Bone Marrow Cells
por: Yang, Jinpu, et al.
Publicado: (2017)

Histone Deacetylase Inhibitory Activity and Antiproliferative Potential of New [6]-Shogaol Derivatives
por: Phaosiri, Chanokbhorn, et al.
Publicado: (2022)

Histone deacetylase inhibitor screening identifies HC toxin as the most effective in intrahepatic cholangiocarcinoma cells
por: ZHOU, WENJIE, et al.
Publicado: (2016)

A Selective Histone Deacetylase Inhibitor Induces Autophagy and Cell Death via SCNN1A Downregulation in Glioblastoma Cells
por: Chang, Hui Hua, et al.
Publicado: (2022)

Histone Deacetylase Inhibitor-Induced Autophagy in Tumor Cells: Implications for p53
por: Mrakovcic, Maria, et al.
Publicado: (2017)

Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma
por: Phimmachanh, Monica, et al.
Publicado: (2020)

Induction of synergistic non-apoptotic cell death by simultaneously targeting proteasomes with bortezomib and histone deacetylase 6 with ricolinostat in head and neck tumor cells
por: Hattori, Kazuhiro, et al.
Publicado: (2021)

Synergistic enhancement of NK cell-mediated cytotoxicity by combination of histone deacetylase inhibitor and ionizing radiation
por: Son, Cheol-Hun, et al.
Publicado: (2014)

Synergistic Interaction of Histone Deacetylase 6- and MEK-Inhibitors in Castration-Resistant Prostate Cancer Cells
por: Corno, Cristina, et al.
Publicado: (2020)

Design, Synthesis, and Antiproliferative Activity of Selective Histone Deacetylases 6 Inhibitors Containing a Tetrahydropyridopyrimidine Scaffold
por: Wang, Bin, et al.
Publicado: (2023)

Histone deacetylase inhibitor trichostatin A and autophagy inhibitor chloroquine synergistically exert anti-tumor activity in H-ras transformed breast epithelial cells
por: Gao, Liang, et al.
Publicado: (2018)

Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors
por: Lapierre, Marion, et al.
Publicado: (2016)

Histone Deacetylase Activity Modulates Alternative Splicing
por: Hnilicová, Jarmila, et al.
Publicado: (2011)

The class II histone deacetylase HDAC4 regulates cognitive, metabolic and endocrine functions through its expression in osteoblasts
por: Makinistoglu, Munevver Parla, et al.
Publicado: (2014)

Inhibition of phospholipase D2 augments histone deacetylase inhibitor-induced cell death in breast cancer cells
por: Hwang, Won Chan, et al.
Publicado: (2020)

Synergistic Anticancer Effect of Glycolysis and Histone Deacetylases Inhibitors in a Glioblastoma Model
por: Pająk, Beata, et al.
Publicado: (2021)

Synergistic association of resveratrol and histone deacetylase inhibitors as treatment in amyotrophic lateral sclerosis
por: Parrella, Edoardo, et al.
Publicado: (2022)

Histone deacetylase-mediated tumor microenvironment characteristics and synergistic immunotherapy in gastric cancer
por: Lin, Yilin, et al.
Publicado: (2023)

Antiproliferative and apoptotic effects of xanthohumol in cholangiocarcinoma
por: Walden, Daniel, et al.
Publicado: (2017)

Genistein cooperates with the histone deacetylase inhibitor vorinostat to induce cell death in prostate cancer cells
por: Phillip, Cornel J, et al.
Publicado: (2012)

Blocking autophagy overcomes resistance to dual histone deacetylase and proteasome inhibition in gynecologic cancer
por: Bi, Jianling, et al.
Publicado: (2022)

Synthesis and biological evaluation of novel quinolone derivatives dual targeting histone deacetylase and tubulin polymerization as antiproliferative agents
por: Wang, Xuan, et al.
Publicado: (2018)

Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy
por: Stankov, Metodi V., et al.
Publicado: (2013)

Possible Role of Autophagy in the Treatment of Pancreatic Cancer with Histone Deacetylase Inhibitors
por: Rikiishi, Hidemi
Publicado: (2010)

Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates
por: Yao, Ya-Li, et al.
Publicado: (2011)

The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses
por: Moreira, José Manuel Afonso, et al.
Publicado: (2003)

Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition
por: Flatmark, Kjersti, et al.
Publicado: (2006)

Histone deacetylase 3 indirectly modulates tubulin acetylation
por: Bacon, Travis, et al.
Publicado: (2015)

Role of Natural Products in Modulating Histone Deacetylases in Cancer
por: Merarchi, Myriam, et al.
Publicado: (2019)

Histone deacetylases modulate resistance to the therapy in lung cancer
por: Contreras-Sanzón, Estefanía, et al.
Publicado: (2022)

The Novel Class IIa Selective Histone Deacetylase Inhibitor YAK540 Is Synergistic with Bortezomib in Leukemia Cell Lines
por: Bollmann, Lukas M., et al.
Publicado: (2022)

BRD4 inhibitor and histone deacetylase inhibitor synergistically inhibit the proliferation of gallbladder cancer in vitro and in vivo
por: Liu, Shilei, et al.
Publicado: (2019)

Histone deacetylase inhibitor MGCD0103 causes cell cycle arrest, apoptosis, and autophagy in liver cancer cells
por: Liao, Bo, et al.
Publicado: (2020)

Role of Histone Deacetylases in T-Cell Development and Function
por: Pieniawska, Monika, et al.
Publicado: (2022)

Histone Deacetylases and Their Inhibition in Candida Species
por: Garnaud, Cécile, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_vtmmkfu5hg4jj7hdniqmmfjg85