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Sequential Unfolding Mechanisms of Monomeric Caspases
[Image: see text] Caspases are evolutionarily conserved cysteinyl proteases that are integral in cell development and apoptosis. All apoptotic caspases evolved from a common ancestor into two distinct subfamilies with either monomeric (initiators) or dimeric (effectors) oligomeric states. The regula...
Autores principales: | Joglekar, Isha, Clark, A. Clay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286309/ https://www.ncbi.nlm.nih.gov/pubmed/37337671 http://dx.doi.org/10.1021/acs.biochem.3c00004 |
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