Ogt-mediated O-GlcNAcylation inhibits astrocytes activation through modulating NF-κB signaling pathway

Previous studies have shown that Ogt-mediated O-GlcNAcylation is essential for neuronal development and function. However, the function of O-GlcNAc transferase (Ogt) and O-GlcNAcylation in astrocytes remains largely unknown. Here we show that Ogt deficiency induces inflammatory activation of astrocy...

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Detalles Bibliográficos
Autores principales: Dong, Xiaoxue, Shu, Liqi, Zhang, Jinyu, Yang, Xu, Cheng, Xuejun, Zhao, Xingsen, Qu, Wenzheng, Zhu, Qiang, Shou, Yikai, Peng, Guoping, Sun, Binggui, Yi, Wen, Shu, Qiang, Li, Xuekun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286367/
https://www.ncbi.nlm.nih.gov/pubmed/37349834
http://dx.doi.org/10.1186/s12974-023-02824-8

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