Enhancer-driven transcription of MCM8 by E2F4 promotes ATR pathway activation and glioma stem cell characteristics

BACKGROUND: Glioma stem cells (GSCs) are responsible for glioma recurrence and drug resistance, yet the mechanisms underlying their maintenance remains unclear. This study aimed to identify enhancer-controlled genes involved in GSCs maintenance and elucidate the mechanisms underlying their regulatio...

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Detalles Bibliográficos
Autores principales: Sun, Yu-meng, Zhang, Yi-meng, Shi, Hai-liang, Yang, Song, Zhao, Yin-long, Liu, Hong-jiang, Li, Chen, Liu, Hong-lei, Yang, Ji-peng, Song, Jian, Sun, Guo-zhu, Yang, Jian-kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286446/
https://www.ncbi.nlm.nih.gov/pubmed/37349788
http://dx.doi.org/10.1186/s41065-023-00292-x

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