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A novel classification, management and long-term outcomes of coronary artery involvement in acute aortic dissection

BACKGROUND: To introduce a new and simple classification and management of coronary artery involvement in aortic dissection and report results. METHODS: Coronary artery involvement was classified into two types according to the integrity of coronary intima: simple lesion (type S) and complex lesion...

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Autores principales: Chang, Yi, Guo, Hongwei, Yu, Cuntao, Sun, Xiaogang, Yang, Kan, Qian, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286453/
https://www.ncbi.nlm.nih.gov/pubmed/37344803
http://dx.doi.org/10.1186/s12872-023-03301-z
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author Chang, Yi
Guo, Hongwei
Yu, Cuntao
Sun, Xiaogang
Yang, Kan
Qian, Xiangyang
author_facet Chang, Yi
Guo, Hongwei
Yu, Cuntao
Sun, Xiaogang
Yang, Kan
Qian, Xiangyang
author_sort Chang, Yi
collection PubMed
description BACKGROUND: To introduce a new and simple classification and management of coronary artery involvement in aortic dissection and report results. METHODS: Coronary artery involvement was classified into two types according to the integrity of coronary intima: simple lesion (type S) and complex lesion (type C). Complex lesions were treated by CABG and simple lesions were treated by ostial repair or reimplantation. Data were collected and analyzed retrospectively. RESULTS: From January 2010 to December 2019, 267 consecutive patients were enrolled in the study, and among them complex lesions occurred in 27 patients (11.1%) and simple lesions was found in 240 patients(89.9%). Eleven untreated vessels with simple lesion were found to be involved again in the same operation and treated by CABG. The two type groups had comparable operative mortality (type S vs. type C, 9.6% vs. 18.5%, P = 0.28). 221 patients received follow-up with a median duration of 52 months. The overall survival rates at 1, 5, and 10 years postoperatively were 88.9%, 85.7%, and 79.8% in type S group and 79.2%, 79.2%, and 79.2% in type C group, respectively (P = 0.47). For the patients who received CABG and survived at discharge, radiographic follow-up with a median duration of 28 (IQR 7-55.5) months showed the freedom from occlusion of vein graft at 1, 5, and 10 years postoperatively were 87.5%, 70.0%, 28.0%. CONCLUSIONS: According to the new classification, two types of lesions could be treated by corresponding methods with satisfactory early and long-term results. Unrepaired coronary artery was at a risk of re-involvement. Vein graft onto arteries without atherosclerosis still had a high occlusion rate. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-023-03301-z.
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spelling pubmed-102864532023-06-23 A novel classification, management and long-term outcomes of coronary artery involvement in acute aortic dissection Chang, Yi Guo, Hongwei Yu, Cuntao Sun, Xiaogang Yang, Kan Qian, Xiangyang BMC Cardiovasc Disord Research BACKGROUND: To introduce a new and simple classification and management of coronary artery involvement in aortic dissection and report results. METHODS: Coronary artery involvement was classified into two types according to the integrity of coronary intima: simple lesion (type S) and complex lesion (type C). Complex lesions were treated by CABG and simple lesions were treated by ostial repair or reimplantation. Data were collected and analyzed retrospectively. RESULTS: From January 2010 to December 2019, 267 consecutive patients were enrolled in the study, and among them complex lesions occurred in 27 patients (11.1%) and simple lesions was found in 240 patients(89.9%). Eleven untreated vessels with simple lesion were found to be involved again in the same operation and treated by CABG. The two type groups had comparable operative mortality (type S vs. type C, 9.6% vs. 18.5%, P = 0.28). 221 patients received follow-up with a median duration of 52 months. The overall survival rates at 1, 5, and 10 years postoperatively were 88.9%, 85.7%, and 79.8% in type S group and 79.2%, 79.2%, and 79.2% in type C group, respectively (P = 0.47). For the patients who received CABG and survived at discharge, radiographic follow-up with a median duration of 28 (IQR 7-55.5) months showed the freedom from occlusion of vein graft at 1, 5, and 10 years postoperatively were 87.5%, 70.0%, 28.0%. CONCLUSIONS: According to the new classification, two types of lesions could be treated by corresponding methods with satisfactory early and long-term results. Unrepaired coronary artery was at a risk of re-involvement. Vein graft onto arteries without atherosclerosis still had a high occlusion rate. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-023-03301-z. BioMed Central 2023-06-21 /pmc/articles/PMC10286453/ /pubmed/37344803 http://dx.doi.org/10.1186/s12872-023-03301-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Chang, Yi
Guo, Hongwei
Yu, Cuntao
Sun, Xiaogang
Yang, Kan
Qian, Xiangyang
A novel classification, management and long-term outcomes of coronary artery involvement in acute aortic dissection
title A novel classification, management and long-term outcomes of coronary artery involvement in acute aortic dissection
title_full A novel classification, management and long-term outcomes of coronary artery involvement in acute aortic dissection
title_fullStr A novel classification, management and long-term outcomes of coronary artery involvement in acute aortic dissection
title_full_unstemmed A novel classification, management and long-term outcomes of coronary artery involvement in acute aortic dissection
title_short A novel classification, management and long-term outcomes of coronary artery involvement in acute aortic dissection
title_sort novel classification, management and long-term outcomes of coronary artery involvement in acute aortic dissection
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286453/
https://www.ncbi.nlm.nih.gov/pubmed/37344803
http://dx.doi.org/10.1186/s12872-023-03301-z
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