A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores

BACKGROUND: More than 75 common variant loci account for only a portion of the heritability for Alzheimer’s disease (AD). A more complete understanding of the genetic basis of AD can be deduced by exploring associations with AD-related endophenotypes. METHODS: We conducted genome-wide scans for cogn...

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Detalles Bibliográficos
Autores principales: Kang, Moonil, Ang, Ting Fang Alvin, Devine, Sherral A., Sherva, Richard, Mukherjee, Shubhabrata, Trittschuh, Emily H., Gibbons, Laura E., Scollard, Phoebe, Lee, Michael, Choi, Seo-Eun, Klinedinst, Brandon, Nakano, Connie, Dumitrescu, Logan C., Durant, Alaina, Hohman, Timothy J., Cuccaro, Michael L., Saykin, Andrew J., Kukull, Walter A., Bennett, David A., Wang, Li-San, Mayeux, Richard P., Haines, Jonathan L., Pericak-Vance, Margaret A., Schellenberg, Gerard D., Crane, Paul K., Au, Rhoda, Lunetta, Kathryn L., Mez, Jesse B., Farrer, Lindsay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286470/
https://www.ncbi.nlm.nih.gov/pubmed/37349795
http://dx.doi.org/10.1186/s13024-023-00633-4

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