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Host Lipid Transport Protein ORP1 Is Necessary for Coxiella burnetii Growth and Vacuole Expansion in Macrophages

Coxiella burnetii is an intracellular bacterium that causes the human disease Q fever. C. burnetii forms a large, acidic Coxiella-containing vacuole (CCV) and uses a type 4B secretion system to secrete effector proteins into the host cell cytoplasm. While the CCV membrane is rich in sterols, cholest...

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Detalles Bibliográficos
Autores principales: Schuler, Baleigh, Sladek, Margaret, Gilk, Stacey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286706/
https://www.ncbi.nlm.nih.gov/pubmed/37017523
http://dx.doi.org/10.1128/msphere.00104-23

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