Sulfatinib, a novel multi-targeted tyrosine kinase inhibitor of FGFR1, CSF1R, and VEGFR1–3, suppresses osteosarcoma proliferation and invasion via dual role in tumor cells and tumor microenvironment

INTRODUCTION: Tumor progression is driven by intrinsic malignant behaviors caused by gene mutation or epigenetic modulation, as well as crosstalk with the components in the tumor microenvironment (TME). Considering the current understanding of the tumor microenvironment, targeting the immunomodulato...

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Detalles Bibliográficos
Autores principales: Liao, Song, Li, Jianxiong, Gao, Song, Han, Yuchen, Han, Xinli, Wu, Yanan, Bi, Jingyou, Xu, Meng, Bi, Wenzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286821/
https://www.ncbi.nlm.nih.gov/pubmed/37361567
http://dx.doi.org/10.3389/fonc.2023.1158857

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