Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis

Polycomb repressive complex (PRC) 1 regulates stem cell fate by mediating mono-ubiquitination of histone H2A at lysine 119. While canonical PRC1 is critical for hematopoietic stem and progenitor cell (HSPC) maintenance, the role of non-canonical PRC1 in hematopoiesis remains elusive. PRC1.1, a non-c...

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Detalles Bibliográficos
Autores principales: Nakajima-Takagi, Yaeko, Oshima, Motohiko, Takano, Junichiro, Koide, Shuhei, Itokawa, Naoki, Uemura, Shun, Yamashita, Masayuki, Andoh, Shohei, Aoyama, Kazumasa, Isshiki, Yusuke, Shinoda, Daisuke, Saraya, Atsunori, Arai, Fumio, Yamaguchi, Kiyoshi, Furukawa, Yoichi, Koseki, Haruhiko, Ikawa, Tomokatsu, Iwama, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287155/
https://www.ncbi.nlm.nih.gov/pubmed/37266576
http://dx.doi.org/10.7554/eLife.83004

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