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Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability

Degradation of most yeast mRNAs involves decapping by Dcp1/Dcp2. DEAD-box protein Dhh1 has been implicated as an activator of decapping, in coupling codon non-optimality to enhanced degradation, and as a translational repressor, but its functions in cells are incompletely understood. RNA-Seq analyse...

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Detalles Bibliográficos
Autores principales: Vijjamarri, Anil Kumar, Niu, Xiao, Vandermeulen, Matthew D, Onu, Chisom, Zhang, Fan, Qiu, Hongfang, Gupta, Neha, Gaikwad, Swati, Greenberg, Miriam L, Cullen, Paul J, Lin, Zhenguo, Hinnebusch, Alan G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287164/
https://www.ncbi.nlm.nih.gov/pubmed/37266577
http://dx.doi.org/10.7554/eLife.85545