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Discussion on the Mechanism of Gandoufumu Decoction Attenuates Liver Damage of Wilson's Disease by Inhibiting Autophagy through the PI3K/Akt/mTOR Pathway Based on Network Pharmacology and Experimental Verification

BACKGROUND: Gandoufumu decoction (GDFMD) is a traditional Chinese medicine that has been widely used to treat Wilson's disease (WD) liver damage patients. However, its specific molecular mechanism currently remains unclear. Autophagy as a key contributor to WD liver damage has been intensely re...

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Detalles Bibliográficos
Autores principales: Tang, Lulu, Zhao, Chenling, Zhang, Jing, Dong, Ting, Chen, Huaizhen, Wei, Taohua, Wang, Jiuxiang, Yang, Wenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287518/
https://www.ncbi.nlm.nih.gov/pubmed/37362448
http://dx.doi.org/10.1155/2023/3236911