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Discussion on the Mechanism of Gandoufumu Decoction Attenuates Liver Damage of Wilson's Disease by Inhibiting Autophagy through the PI3K/Akt/mTOR Pathway Based on Network Pharmacology and Experimental Verification
BACKGROUND: Gandoufumu decoction (GDFMD) is a traditional Chinese medicine that has been widely used to treat Wilson's disease (WD) liver damage patients. However, its specific molecular mechanism currently remains unclear. Autophagy as a key contributor to WD liver damage has been intensely re...
Autores principales: | Tang, Lulu, Zhao, Chenling, Zhang, Jing, Dong, Ting, Chen, Huaizhen, Wei, Taohua, Wang, Jiuxiang, Yang, Wenming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287518/ https://www.ncbi.nlm.nih.gov/pubmed/37362448 http://dx.doi.org/10.1155/2023/3236911 |
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