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Multiplex genome engineering in Clostridium beijerinckii NCIMB 8052 using CRISPR-Cas12a
Clostridium species are re-emerging as biotechnological workhorses for industrial acetone–butanol–ethanol production. This re-emergence is largely due to advances in fermentation technologies but also due to advances in genome engineering and re-programming of the native metabolism. Several genome e...
Autores principales: | Patinios, Constantinos, de Vries, Stijn T., Diallo, Mamou, Lanza, Lucrezia, Verbrugge, Pepijn L. J. V. Q., López-Contreras, Ana M., van der Oost, John, Weusthuis, Ruud A., Kengen, Servé W. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287719/ https://www.ncbi.nlm.nih.gov/pubmed/37349508 http://dx.doi.org/10.1038/s41598-023-37220-y |
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