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Enteral administration of the protease inhibitor gabexate mesilate preserves vascular function in experimental trauma/hemorrhagic shock

Preserving vascular function is crucial for preventing multiorgan failure and death in ischemic and low-pressure states such as trauma/hemorrhagic shock (T/HS). It has recently been reported that inhibiting circulating proteases released from the bowel to the circulation during T/HS may preserve vas...

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Detalles Bibliográficos
Autores principales: J. D. Moreira, Nathalia, dos Santos, Fernando, Li, Joyce B., Aletti, Federico, Irigoyen, Maria Claudia C., Kistler, Erik B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287748/
https://www.ncbi.nlm.nih.gov/pubmed/37349360
http://dx.doi.org/10.1038/s41598-023-36021-7