Structural analysis of the Candida albicans mitochondrial DNA maintenance factor Gcf1p reveals a dynamic DNA-bridging mechanism

The compaction of mitochondrial DNA (mtDNA) is regulated by architectural HMG-box proteins whose limited cross-species similarity suggests diverse underlying mechanisms. Viability of Candida albicans, a human antibiotic-resistant mucosal pathogen, is compromised by altering mtDNA regulators. Among t...

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Detalles Bibliográficos
Autores principales: Tarrés-Solé, Aleix, Battistini, Federica, Gerhold, Joachim M, Piétrement, Olivier, Martínez-García, Belén, Ruiz-López, Elena, Lyonnais, Sébastien, Bernadó, Pau, Roca, Joaquim, Orozco, Modesto, Le Cam, Eric, Sedman, Juhan, Solà, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287934/
https://www.ncbi.nlm.nih.gov/pubmed/37207342
http://dx.doi.org/10.1093/nar/gkad397

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