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Dynamic accumulation of cyclobutane pyrimidine dimers and its response to changes in DNA conformation

Photochemical dimerization of adjacent pyrimidines is fundamental to the creation of mutagenic hotspots caused by ultraviolet light. Distribution of the resulting lesions (cyclobutane pyrimidine dimers, CPDs) is already known to be highly variable in cells, and in vitro models have implicated DNA co...

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Detalles Bibliográficos
Autores principales:	Moirangthem, Ravina, Gamage, Manusha N, Rokita, Steven E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287945/ https://www.ncbi.nlm.nih.gov/pubmed/37207339 http://dx.doi.org/10.1093/nar/gkad434

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