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Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation

The CTP nucleotide is a key precursor of nucleic acids metabolism essential for DNA replication. De novo CTP production relies on CTP synthetases 1 and 2 (CTPS1 and CTPS2) that catalyze the conversion of UTP into CTP. CTP synthetase activity is high in proliferating cells including cancer cells; how...

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Detalles Bibliográficos
Autores principales:	Minet, Norbert, Boschat, Anne-Claire, Lane, Rebecca, Laughton, David, Beer, Philip, Asnagli, Hélène, Soudais, Claire, Bourne, Tim, Fischer, Alain, Martin, Emmanuel, Latour, Sylvain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288033/ https://www.ncbi.nlm.nih.gov/pubmed/37348953 http://dx.doi.org/10.26508/lsa.202302066

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