A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases

OBJECTIVES: Inflammasomes induce maturation of the inflammatory cytokines IL‐1β and IL‐18, whose activity is associated with the pathophysiology of a wide range of infectious and inflammatory diseases. As validated therapeutic targets for the treatment of acute and chronic inflammatory diseases, the...

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Detalles Bibliográficos
Autores principales: Docherty, Callum AH, Fernando, Anuruddika J, Rosli, Sarah, Lam, Maggie, Dolle, Roland E, Navia, Manuel A, Farquhar, Ronald, La France, Danny, Tate, Michelle D, Murphy, Christopher K, Rossi, Adriano G, Mansell, Ashley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288073/
https://www.ncbi.nlm.nih.gov/pubmed/37360982
http://dx.doi.org/10.1002/cti2.1455

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