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Topical and systemic GLP-1R agonist administration both rescue retinal ganglion cells in hypertensive glaucoma

Glaucomatous neurodegeneration, a blinding disease affecting millions worldwide, has a need for the exploration of new and effective therapies. Previously, the glucagon-like peptide-1 receptor (GLP-1R) agonist NLY01 was shown to reduce microglia/macrophage activation, rescuing retinal ganglion cells...

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Detalles Bibliográficos
Autores principales:	Lawrence, Emily C. N., Guo, Michelle, Schwartz, Turner D., Wu, Jie, Lu, Jingwen, Nikonov, Sergei, Sterling, Jacob K., Cui, Qi N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288152/ https://www.ncbi.nlm.nih.gov/pubmed/37362000 http://dx.doi.org/10.3389/fncel.2023.1156829

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