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Wnt3a‐Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury (Adv. Sci. 18/2023)

Wnt3a‐Loaded Extracellular Vesicles In article number 2206606, Linzhao Cheng, Senquan Liu, and co‐workers devise a novel approach to deliver hydrophobic Wnt3a by anchoring it to the surface of extracellular vesicles (EVs). The therapeutic functions of engineered EVs are validated by experimental lun...

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Detalles Bibliográficos
Autores principales: Gao, Lei, Sun, Yongping, Zhang, Xinye, Ma, Ding, Xie, An, Wang, Enyu, Cheng, Linzhao, Liu, Senquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288222/
http://dx.doi.org/10.1002/advs.202370116
Descripción
Sumario:Wnt3a‐Loaded Extracellular Vesicles In article number 2206606, Linzhao Cheng, Senquan Liu, and co‐workers devise a novel approach to deliver hydrophobic Wnt3a by anchoring it to the surface of extracellular vesicles (EVs). The therapeutic functions of engineered EVs are validated by experimental lung injury models. EV‐based Wnt signaling activation may represent a valuable therapeutic strategy for tissue regeneration and repair after injury. [Image: see text]