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SP7 gene silencing dampens bone marrow stromal cell hypertrophy, but it also dampens chondrogenesis

For bone marrow stromal cells (BMSC) to be useful in cartilage repair their propensity for hypertrophic differentiation must be overcome. A single day of TGF-β1 stimulation activates intrinsic signaling cascades in BMSCs which subsequently drives both chondrogenic and hypertrophic differentiation. T...

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Detalles Bibliográficos
Autores principales:	Franco, Rose Ann G, McKenna, Eamonn, Robey, Pamela G, Crawford, Ross W, Doran, Michael R, Futrega, Kathryn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288420/ https://www.ncbi.nlm.nih.gov/pubmed/37362901 http://dx.doi.org/10.1177/20417314231177136

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