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Precision oncology with selective RET inhibitor selpercatinib in RET-rearranged cancers

Rearranged during transfection (RET) is a protooncogene that encodes for receptor tyrosine kinase with downstream effects on multiple cellular pathways. Activating RET alterations can occur and lead to uncontrolled cellular proliferation as a hallmark of cancer development. Oncogenic RET fusions are...

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Detalles Bibliográficos
Autores principales:	Gouda, Mohamed A., Subbiah, Vivek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288430/ https://www.ncbi.nlm.nih.gov/pubmed/37360768 http://dx.doi.org/10.1177/17588359231177015

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