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Assessing Iron Status in Chronic Heart Failure Patients by Using Serum Ferritin and Transferrin Saturation Levels: A Cross-Sectional Descriptive Study
Background and objective Chronic heart failure (HF) is a major medical condition worldwide and is associated with significant morbidity and mortality. Chronic HF could be complicated by iron deficiency (ID), and in severe cases, ID anemia, leading to negative HF outcomes even in people on optimal HF...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288524/ https://www.ncbi.nlm.nih.gov/pubmed/37362450 http://dx.doi.org/10.7759/cureus.39425 |
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author | Amaechi, Uchenna M Aiwuyo, Henry O Ewelukwa, Chukwudum Ilerhunmwuwa, Nosakhare Osarenkhoe, John O Kweki, Anthony G Onuwaje, Okoke Eseoghene Mbakwem, Amam Kehinde, Michael |
author_facet | Amaechi, Uchenna M Aiwuyo, Henry O Ewelukwa, Chukwudum Ilerhunmwuwa, Nosakhare Osarenkhoe, John O Kweki, Anthony G Onuwaje, Okoke Eseoghene Mbakwem, Amam Kehinde, Michael |
author_sort | Amaechi, Uchenna M |
collection | PubMed |
description | Background and objective Chronic heart failure (HF) is a major medical condition worldwide and is associated with significant morbidity and mortality. Chronic HF could be complicated by iron deficiency (ID), and in severe cases, ID anemia, leading to negative HF outcomes even in people on optimal HF treatments. ID has been reported to be the most common nutritional deficiency in chronic HF. It is therefore important to study and analyze the relationship between these two variables. Identifying and treating the comorbidity of ID in chronic HF may help improve the treatment outcomes of chronic HF. In this study, we aimed to determine the iron status of chronic HF patients by using serum ferritin (SF) and transferrin saturation (TSAT). Materials and methods A cross-sectional descriptive study was conducted involving 88 Nigerian patients with chronic HF at the Lagos University Teaching Hospital (LUTH). The participants were evaluated based on their laboratory findings. Results ID was found in 34% of chronic HF patients. Of them, 17% had absolute ID while 17% had functional ID. Conclusion ID was present in about one-third of the chronic HF patients. It was more common and worse in patients belonging to advanced HF functional classes. |
format | Online Article Text |
id | pubmed-10288524 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-102885242023-06-24 Assessing Iron Status in Chronic Heart Failure Patients by Using Serum Ferritin and Transferrin Saturation Levels: A Cross-Sectional Descriptive Study Amaechi, Uchenna M Aiwuyo, Henry O Ewelukwa, Chukwudum Ilerhunmwuwa, Nosakhare Osarenkhoe, John O Kweki, Anthony G Onuwaje, Okoke Eseoghene Mbakwem, Amam Kehinde, Michael Cureus Cardiology Background and objective Chronic heart failure (HF) is a major medical condition worldwide and is associated with significant morbidity and mortality. Chronic HF could be complicated by iron deficiency (ID), and in severe cases, ID anemia, leading to negative HF outcomes even in people on optimal HF treatments. ID has been reported to be the most common nutritional deficiency in chronic HF. It is therefore important to study and analyze the relationship between these two variables. Identifying and treating the comorbidity of ID in chronic HF may help improve the treatment outcomes of chronic HF. In this study, we aimed to determine the iron status of chronic HF patients by using serum ferritin (SF) and transferrin saturation (TSAT). Materials and methods A cross-sectional descriptive study was conducted involving 88 Nigerian patients with chronic HF at the Lagos University Teaching Hospital (LUTH). The participants were evaluated based on their laboratory findings. Results ID was found in 34% of chronic HF patients. Of them, 17% had absolute ID while 17% had functional ID. Conclusion ID was present in about one-third of the chronic HF patients. It was more common and worse in patients belonging to advanced HF functional classes. Cureus 2023-05-24 /pmc/articles/PMC10288524/ /pubmed/37362450 http://dx.doi.org/10.7759/cureus.39425 Text en Copyright © 2023, Amaechi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Amaechi, Uchenna M Aiwuyo, Henry O Ewelukwa, Chukwudum Ilerhunmwuwa, Nosakhare Osarenkhoe, John O Kweki, Anthony G Onuwaje, Okoke Eseoghene Mbakwem, Amam Kehinde, Michael Assessing Iron Status in Chronic Heart Failure Patients by Using Serum Ferritin and Transferrin Saturation Levels: A Cross-Sectional Descriptive Study |
title | Assessing Iron Status in Chronic Heart Failure Patients by Using Serum Ferritin and Transferrin Saturation Levels: A Cross-Sectional Descriptive Study |
title_full | Assessing Iron Status in Chronic Heart Failure Patients by Using Serum Ferritin and Transferrin Saturation Levels: A Cross-Sectional Descriptive Study |
title_fullStr | Assessing Iron Status in Chronic Heart Failure Patients by Using Serum Ferritin and Transferrin Saturation Levels: A Cross-Sectional Descriptive Study |
title_full_unstemmed | Assessing Iron Status in Chronic Heart Failure Patients by Using Serum Ferritin and Transferrin Saturation Levels: A Cross-Sectional Descriptive Study |
title_short | Assessing Iron Status in Chronic Heart Failure Patients by Using Serum Ferritin and Transferrin Saturation Levels: A Cross-Sectional Descriptive Study |
title_sort | assessing iron status in chronic heart failure patients by using serum ferritin and transferrin saturation levels: a cross-sectional descriptive study |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288524/ https://www.ncbi.nlm.nih.gov/pubmed/37362450 http://dx.doi.org/10.7759/cureus.39425 |
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