Spike-protein proteolytic antibodies in COVID-19 convalescent plasma contribute to SARS-CoV-2 neutralization

Understanding the mechanisms of antibody-mediated neutralization of SARS-CoV-2 is critical in combating the COVID-19 pandemic. Based on previous reports of antibody catalysis, we investigated the proteolysis of spike (S) by antibodies in COVID-19 convalescent plasma (CCP) and its contribution to vir...

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Detalles Bibliográficos
Autores principales: McConnell, Scott A., Sachithanandham, Jaiprasath, Mudrak, Nathan J., Zhu, Xianming, Farhang, Parsa Alba, Cordero, Radames J.B., Wear, Maggie P., Shapiro, Janna R., Park, Han-Sol, Klein, Sabra L., Tobian, Aaron A.R., Bloch, Evan M., Sullivan, David J., Pekosz, Andrew, Casadevall, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288624/
https://www.ncbi.nlm.nih.gov/pubmed/37354908
http://dx.doi.org/10.1016/j.chembiol.2023.05.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288624/
https://www.ncbi.nlm.nih.gov/pubmed/37354908
http://dx.doi.org/10.1016/j.chembiol.2023.05.011

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