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Dynamic interactome of the MHC I peptide loading complex in human dendritic cells

Dendritic cells (DCs) orchestrate immune responses by presenting antigenic peptides on major histocompatibility complex (MHC) molecules to T cells. Antigen processing and presentation via MHC I rely on the peptide-loading complex (PLC), a supramolecular machinery assembled around the transporter ass...

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Detalles Bibliográficos
Autores principales: Barends, Martina, Koller, Nicole, Schölz, Christian, Durán, Verónica, Bošnjak, Berislav, Becker, Jennifer, Döring, Marius, Blees, Hanna, Förster, Reinhold, Kalinke, Ulrich, Tampé, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288655/
https://www.ncbi.nlm.nih.gov/pubmed/37307450
http://dx.doi.org/10.1073/pnas.2219790120