Single-cell analysis reveals HBV-specific PD-1(+)CD8(+) TRM cells in tumor borders are associated with HBV-related hepatic damage and fibrosis in HCC patients

Immune checkpoint blockade (ICB) treatment of hepatocellular carcinoma (HCC) patients with hepatitis B virus (HBV) infection may activate viral-specific T cells to attack HBV infected hepatocytes and thus induce immune-related liver injury. Therefore, it is important to deeply understand the impacts...

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Detalles Bibliográficos
Autores principales: Liu, Lulu, Liu, Junwei, Li, Pan, Luo, Jijun, Qin, Rui, Peng, Qiao, Li, Bin, Wei, Xuyong, Wang, Tian, Shi, Hongyu, Wang, Ming-Da, Li, Chao, Fang, Weijia, Chen, Wei, Xu, Xiao, Yang, Tian, Yin, Weiwei, Zeng, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288678/
https://www.ncbi.nlm.nih.gov/pubmed/37353792
http://dx.doi.org/10.1186/s13046-023-02710-4

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