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METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing

BACKGROUND: Endometriosis (EMs), the ectopic planting of functional endometrium outside of the uterus, is a leading cause of infertility and pelvic pain. As a fundamental mRNA modification, N6-methyladenosine (m6A) participates in various pathological processes. However, the role of m6A RNA modifica...

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Detalles Bibliográficos
Autores principales: Wang, Xiaotong, Wang, Jing, Zhao, Xibo, Wu, Han, Li, Jixin, Cheng, Yan, Guo, Qiuyan, Cao, Xuejiao, Liang, Tian, Sun, Liyuan, Zhang, Guangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288727/
https://www.ncbi.nlm.nih.gov/pubmed/37353804
http://dx.doi.org/10.1186/s12967-023-04209-0

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