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Revisiting the neuroinflammation hypothesis in Alzheimer’s disease: a focus on the druggability of current targets

Alzheimer’s disease (AD) is the most common form of neurodegenerative disease and disability in the elderly; it is estimated to account for 60%–70% of all cases of dementia worldwide. The most relevant mechanistic hypothesis to explain AD symptoms is neurotoxicity induced by aggregated amyloid-β pep...

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Detalles Bibliográficos
Autores principales: Wong-Guerra, Maylin, Calfio, Camila, Maccioni, Ricardo B., Rojo, Leonel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288808/
https://www.ncbi.nlm.nih.gov/pubmed/37361208
http://dx.doi.org/10.3389/fphar.2023.1161850