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Predictors of health-related quality of life in outpatients with coronary heart disease

INTRODUCTION: Health-related quality of life (HRQoL) is an important treatment target in patients with coronary heart disease (CHD) and is associated with poor outcomes. Therefore, it is of clinical importance to identify the key determinants of HRQoL among these patients. There is, however, limited...

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Autores principales: Frøjd, Lars Aastebøl, Munkhaugen, John, Papageorgiou, Costas, Sverre, Elise, Moum, Torbjørn, Dammen, Toril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289018/
https://www.ncbi.nlm.nih.gov/pubmed/37359852
http://dx.doi.org/10.3389/fpsyg.2023.1119093
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author Frøjd, Lars Aastebøl
Munkhaugen, John
Papageorgiou, Costas
Sverre, Elise
Moum, Torbjørn
Dammen, Toril
author_facet Frøjd, Lars Aastebøl
Munkhaugen, John
Papageorgiou, Costas
Sverre, Elise
Moum, Torbjørn
Dammen, Toril
author_sort Frøjd, Lars Aastebøl
collection PubMed
description INTRODUCTION: Health-related quality of life (HRQoL) is an important treatment target in patients with coronary heart disease (CHD) and is associated with poor outcomes. Therefore, it is of clinical importance to identify the key determinants of HRQoL among these patients. There is, however, limited knowledge of how a comprehensive set of psychosocial factors influence HRQoL. We aimed to determine the relative associations of clinical and psychosocial factors with mental and physical components of HRQoL in a sample of CHD outpatients. METHODS: This cross-sectional study included 1,042 patients 2–36 (mean 16) months after a CHD event recruited from two general Norwegian hospitals with a combined catchment area making up 7% of the Norwegian population, representative with regards to demographic and clinical factors. We collected data on HRQoL, demographics, comorbidities, coronary risk factors, and psychosocial factors. HRQoL was assessed using the Short Form 12 (SF12), which comprises a Mental Component Scale (MCS), and the Physical Component Scale (PCS). Crude and multi-adjusted linear regression analyses were used to investigate the association between covariates and MCS and PCS. RESULTS: Mean age was 61 [standard deviation (SD) 10] years, 20% were females, 18% had type D personality, 20% significant depression symptoms, 14% significant symptoms of anxiety whereas 45% reported insomnia. The presence of type D personality (β: −0.19), significant symptoms of depression (β: −0.15), and the presence of insomnia (β: −0.13) were negatively associated with MCS, but not PCS in multi-adjusted analyses. The presence of chronic kidney disease (β: −0.11) was associated with reduced MCS, whereas the presence of chronic obstructive pulmonary disease (β: −0.08) and low physical activity (β: −0.14) were negatively associated with PCS. Younger age was associated with lower MCS, whereas older age was associated with lower PCS. DISCUSSION: We conclude that Type D personality, depressive symptoms, insomnia, and chronic kidney disease were the strongest determinants of the mental component of HRQoL. Assessing and managing these psychological factors among CHD outpatients may improve their mental HRQoL.
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spelling pubmed-102890182023-06-24 Predictors of health-related quality of life in outpatients with coronary heart disease Frøjd, Lars Aastebøl Munkhaugen, John Papageorgiou, Costas Sverre, Elise Moum, Torbjørn Dammen, Toril Front Psychol Psychology INTRODUCTION: Health-related quality of life (HRQoL) is an important treatment target in patients with coronary heart disease (CHD) and is associated with poor outcomes. Therefore, it is of clinical importance to identify the key determinants of HRQoL among these patients. There is, however, limited knowledge of how a comprehensive set of psychosocial factors influence HRQoL. We aimed to determine the relative associations of clinical and psychosocial factors with mental and physical components of HRQoL in a sample of CHD outpatients. METHODS: This cross-sectional study included 1,042 patients 2–36 (mean 16) months after a CHD event recruited from two general Norwegian hospitals with a combined catchment area making up 7% of the Norwegian population, representative with regards to demographic and clinical factors. We collected data on HRQoL, demographics, comorbidities, coronary risk factors, and psychosocial factors. HRQoL was assessed using the Short Form 12 (SF12), which comprises a Mental Component Scale (MCS), and the Physical Component Scale (PCS). Crude and multi-adjusted linear regression analyses were used to investigate the association between covariates and MCS and PCS. RESULTS: Mean age was 61 [standard deviation (SD) 10] years, 20% were females, 18% had type D personality, 20% significant depression symptoms, 14% significant symptoms of anxiety whereas 45% reported insomnia. The presence of type D personality (β: −0.19), significant symptoms of depression (β: −0.15), and the presence of insomnia (β: −0.13) were negatively associated with MCS, but not PCS in multi-adjusted analyses. The presence of chronic kidney disease (β: −0.11) was associated with reduced MCS, whereas the presence of chronic obstructive pulmonary disease (β: −0.08) and low physical activity (β: −0.14) were negatively associated with PCS. Younger age was associated with lower MCS, whereas older age was associated with lower PCS. DISCUSSION: We conclude that Type D personality, depressive symptoms, insomnia, and chronic kidney disease were the strongest determinants of the mental component of HRQoL. Assessing and managing these psychological factors among CHD outpatients may improve their mental HRQoL. Frontiers Media S.A. 2023-06-09 /pmc/articles/PMC10289018/ /pubmed/37359852 http://dx.doi.org/10.3389/fpsyg.2023.1119093 Text en Copyright © 2023 Frøjd, Munkhaugen, Papageorgiou, Sverre, Moum and Dammen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychology
Frøjd, Lars Aastebøl
Munkhaugen, John
Papageorgiou, Costas
Sverre, Elise
Moum, Torbjørn
Dammen, Toril
Predictors of health-related quality of life in outpatients with coronary heart disease
title Predictors of health-related quality of life in outpatients with coronary heart disease
title_full Predictors of health-related quality of life in outpatients with coronary heart disease
title_fullStr Predictors of health-related quality of life in outpatients with coronary heart disease
title_full_unstemmed Predictors of health-related quality of life in outpatients with coronary heart disease
title_short Predictors of health-related quality of life in outpatients with coronary heart disease
title_sort predictors of health-related quality of life in outpatients with coronary heart disease
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289018/
https://www.ncbi.nlm.nih.gov/pubmed/37359852
http://dx.doi.org/10.3389/fpsyg.2023.1119093
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